NCT03690921View on ClinicalTrials.gov

Linear Energy Transfer (LET)-Optimized Intensity Modulated Proton Therapy (IMPT) as a Component of Definitive Chemoradiation for Newly Diagnosed Squamous Cell Carcinoma of the Anal Canal: a Feasibility Trial

PHASE2CompletedINTERVENTIONAL
Enrollment

8

Participants

Timeline

Start Date

November 8, 2018

Primary Completion Date

June 3, 2022

Study Completion Date

June 3, 2022

Conditions
Anal Canal Squamous Cell CarcinomaStage I Anal Cancer AJCC v8Stage II Anal Cancer AJCC v8Stage IIA Anal Cancer AJCC v8Stage IIB Anal Cancer AJCC v8Stage III Anal Cancer AJCC v8Stage IIIA Anal Cancer AJCC v8Stage IIIB Anal Cancer AJCC v8Stage IIIC Anal Cancer AJCC v8
Interventions
DRUG

Cisplatin

Given IV

DRUG

Fluorouracil

Given IV

RADIATION

Linear Energy Transfer-Optimized Intensity Modulated Proton Therapy

Undergo LET-IMPT

PROCEDURE

Quality-of-Life Assessment

Ancillary studies

OTHER

Questionnaire Administration

Ancillary studies

Trial Locations (1)

77030

M D Anderson Cancer Center, Houston

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

M.D. Anderson Cancer Center

OTHER

NCT03690921 - Linear Energy Transfer (LET)-Optimized Intensity Modulated Proton Therapy (IMPT) as a Component of Definitive Chemoradiation for Newly Diagnosed Squamous Cell Carcinoma of the Anal Canal: a Feasibility Trial | Biotech Hunter | Biotech Hunter