NCT03689543 - Estrogen Receptor Beta and Mood | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

May 23, 2019

Primary Completion Date

September 9, 2024

Study Completion Date

September 9, 2024

Conditions

Perimenopause-Related Depression

Interventions

DRUG

Estradiol

Estradiol patch 0.1 mg transdermal every three days for three weeks

DRUG

ER Beta Agonist

Lilly Compound LY500307, a selective estrogen receptor (ER) beta agonist

OTHER

Placebo

Placebo orally once daily

DRUG

Provera

Provera 5 mg orally once a day for one week after completion of randomization

Trial Locations (1)

National Institutes of Health Clinical Center, Bethesda

All Listed Sponsors

lead

National Institute of Mental Health (NIMH)

NIH