Personalized Treatments for Depressive Symptoms in Patients With Advanced Heart Failure

PHASE4CompletedINTERVENTIONAL
Enrollment

494

Participants

Timeline

Start Date

November 9, 2018

Primary Completion Date

October 25, 2021

Study Completion Date

May 6, 2022

Conditions
DepressionHeart Failure
Interventions
BEHAVIORAL

Behavioral Activation Therapy

The therapy group will consist of an introductory in person 50-minute treatment session, followed by 12 weekly telephone 50-minute outpatient treatment sessions, then 3 monthly telephone 50-minute outpatient maintenance sessions. A typical BA session will last 50 minutes and include a review of the previous session and completed daily monitoring record forms, an in-depth discussion of life areas and value, and verbal reinforcement of activity engagement.

DRUG

Medication Management

Collaborative care model will be used. The medication management group will meet with the patient in a one 50 minute in person introductory antidepressant medication treatment session to educate the patient about depression and medication options. Patients will get prescribed a standard of care anti-depressant medication by treating physician, followed by 12 weekly follow up telephone visits, then on a monthly basis for 3 months, and then as needed thereafter.

Trial Locations (1)

90048

Cedars Sinai Medical Center, Los Angeles

All Listed Sponsors
collaborator

Patient-Centered Outcomes Research Institute

OTHER

lead

Cedars-Sinai Medical Center

OTHER

NCT03688100 - Personalized Treatments for Depressive Symptoms in Patients With Advanced Heart Failure | Biotech Hunter | Biotech Hunter