Impact of Probiotics on Oral Microbiota in Older Adults With Dysphagia

EARLY_PHASE1CompletedINTERVENTIONAL
Enrollment

9

Participants

Timeline

Start Date

August 27, 2018

Primary Completion Date

January 21, 2020

Study Completion Date

January 21, 2020

Conditions
Dysphagia
Interventions
DRUG

VSL#3

Probiotics are dietary supplements composed of live microorganisms that are normally found within the human microbiome. Probiotics, specifically Lactobacilli and Streptococcus salivarius, have been shown to alter oral microbial composition and to inhibit oral pathogens that contribute to dental caries and periodontal disease. The probiotic chosen for this study is VSL#3, a blend of 8 strains of bacteria, including Lactobacillus and Streptococcus salivarius. VSL#3 has been well tolerated, with minimal adverse effects. VLS#3 was chosen as the treatment substance for this project due to its successful use in trials examining an array of outcomes and its combination of several strains of bacteria.

Trial Locations (1)

53562

University of Wisconsin-Madison, Madison

All Listed Sponsors
lead

University of Wisconsin, Madison

OTHER

NCT03682094 - Impact of Probiotics on Oral Microbiota in Older Adults With Dysphagia | Biotech Hunter | Biotech Hunter