Interventions for Patients With Alzheimer's Disease and Dysphagia

NAActive, not recruitingINTERVENTIONAL
Enrollment

76

Participants

Timeline

Start Date

September 25, 2020

Primary Completion Date

August 30, 2025

Study Completion Date

November 30, 2025

Conditions
DementiaDysphagiaAlzheimer Disease
Interventions
DEVICE

Isometric tongue strengthening facilitated by Iowa Oral Performance Instrument (IOPI)

An air-filled pressure bulb is placed on the surface of the oral tongue and pressed against the hard palate during exercise. Each patient is given a target pressure value to aim for as determined by the baseline one repetition maximum (1RM) lingual pressures. During week one of the regimen, the target value of each repetition will be 60% of the 1RM. For the remaining seven weeks, the target value will be increased to 80% of the 1RM. At weeks three, five, and seven, the baseline will be re-measured by phone and the 80% target value re-calculated.

DEVICE

Biotene Oral Balance Gel

Participants will be instructed to apply an amount equivalent to about 1 cm of Biotene® Oral Balance Gel with a finger to the tongue and most intensely affected areas of the oral cavity three times a day after brushing their teeth for 8 weeks.

Trial Locations (1)

53705

University of Wisconsin-Madison, Madison

All Listed Sponsors
collaborator

National Institute on Aging (NIA)

NIH

lead

University of Wisconsin, Madison

OTHER