12
Participants
Start Date
April 23, 2018
Primary Completion Date
April 23, 2019
Study Completion Date
May 23, 2019
Ceftriaxone 4g/ 24h
Each individual will be administrated 2 doses of 2 g of ceftriaxone separated for 12 hours. After a wash-out period (5-7 days) the same individuals will receive a single dose 4 g of ceftriaxone. In both cycles, plasma drug concentrations will be measure during 24 hours.
Ceftriaxone 2g/ 12h
Each individual will be administrated 2 doses of 2 g of ceftriaxone separated for 12 hours. After a wash-out period (5-7 days) the same individuals will receive a single dose 4 g of ceftriaxone. In both cycles, plasma drug concentrations will be measure during 24 hours.
University Hospital Virgen del Rocio, Seville
Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
OTHER