Early Versus Differed Arterial Catheterization in Critically Ill Patients With Acute Circulatory Failure:

NACompletedINTERVENTIONAL
Enrollment

1,010

Participants

Timeline

Start Date

November 15, 2018

Primary Completion Date

November 29, 2022

Study Completion Date

February 28, 2023

Conditions
Acute Circulatory Failure
Interventions
PROCEDURE

Non-invasive strategy

"No indwelling arterial catheter insertion will be allowed during the first 28 days, excepted if predefined safety criteria (indicating absolute need of indwelling arterial catheter insertion) are reached.~In the non-invasive group, automated oscillometric monitor will be used to monitor BP (blood pressure)."

PROCEDURE

Control strategy

An indwelling arterial catheter will be inserted as soon as possible (within the first four hours after randomization) and will be maintained except in case of indwelling arterial catheter futility, suspected or proven indwelling arterial catheter related infection or thrombosis (at discretion of attending physician) until day 28 or ICU (Intensive Care Unit) discharge (whichever comes first). After day 28, clinicians may choose to maintain or to remove indwelling arterial catheter.

Trial Locations (9)

Unknown

Intensive care, Argenteuil

Intensive care, Dijon

Intensive care, La Roche-sur-Yon

Intensive care, Montauban

Intensive care, Nantes

Intensive care, Orléans

Intensive care, Poitiers

Intensive care, Strasbourg

Intensive care, Tours

All Listed Sponsors
lead

University Hospital, Tours

OTHER

NCT03680963 - Early Versus Differed Arterial Catheterization in Critically Ill Patients With Acute Circulatory Failure: | Biotech Hunter | Biotech Hunter