The Effect of Antioxidants on Skin Blood Flow During Local Heating

PHASE1CompletedINTERVENTIONAL
Enrollment

44

Participants

Timeline

Start Date

September 7, 2016

Primary Completion Date

October 9, 2017

Study Completion Date

October 9, 2017

Conditions
Cardiovascular DiseasesCardiovascular Risk FactorVasodilation
Interventions
OTHER

Control (Lactated Ringer's)

This intervention is meant to serve as a control by which the experimental sites are compared to, to assess effectiveness.

DRUG

Tempol

This intervention is meant to assess the impact of superoxide on vasodilator responses by scavenging available superoxide.

DRUG

Apocynin

This intervention is meant to assess the impact of NADPH oxidase-derived superoxide on vasodilator responses by inhibiting the enzyme NADPH oxidase.

DRUG

Allopurinol

This intervention is meant to assess the impact of xanthine oxidase-derived superoxide on vasodilator responses by inhibiting the enzyme xanthine oxidase.

Trial Locations (1)

76019

Engineering Research Building, Arlington

All Listed Sponsors
lead

The University of Texas at Arlington

OTHER

NCT03680638 - The Effect of Antioxidants on Skin Blood Flow During Local Heating | Biotech Hunter | Biotech Hunter