Lessening Organ Dysfunction With VITamin C

PHASE3CompletedINTERVENTIONAL
Enrollment

872

Participants

Timeline

Start Date

November 8, 2018

Primary Completion Date

August 15, 2021

Study Completion Date

January 24, 2022

Conditions
SepsisVitamin CIntensive Care UnitCOVID-19PandemicCoronavirus
Interventions
DRUG

Vitamin C

Intravenous vitamin C administered in bolus doses of 50 mg/kg mixed in a 50-mL solution of either dextrose 5% in water (D5W) or normal saline (0.9% NaCl), during 30 to 60 minutes, every 6 hours for 96 hours (i.e. 200 mg/kg/day and 16 doses in total).

OTHER

Control

Dextrose 5% in water (D5W) or normal saline (0.9% NaCl) in a volume to match the vitamin C.

Trial Locations (1)

J1H 5N4

Research Center of the CHUS, Sherbrooke

All Listed Sponsors
collaborator

Lotte & John Hecht Memorial Foundation

OTHER

lead

Université de Sherbrooke

OTHER

NCT03680274 - Lessening Organ Dysfunction With VITamin C | Biotech Hunter | Biotech Hunter