19
Participants
Start Date
October 1, 2018
Primary Completion Date
July 26, 2023
Study Completion Date
July 26, 2023
BQ-788
This intervention is aimed at blocking endothelin type B receptors to assess racial differences during vasoconstriction. The infusion rate will be 2 µl/min
BQ-123
This intervention is aimed at blocking endothelin type A receptors to assess racial differences during vasoconstriction. The infusion rate will be 2 µl/min
L-Arginine
A substrate that is administered to increase endogenous nitric oxide production. The infusion rate will be 2 µl/min
NG Nitro L Arginine Methyl Ester
L-Name is a NOS inhibitor that is administered to each site to allow for the quantification of NO contribution to vasodilation. The infusion rate will be 2 µl/min
Sodium Nitroprusside
SNP will be perfused through each site to induce maximal vasodilation. The infusion rate will be 2 µl/min
Lactated Ringer's
Lactated Ringer will serve as the control site. The infusion rate will be 2 µl/min
Science and Engineering Research and Innovation Building, Arlington
The University of Texas at Arlington
OTHER