Improving Cognition in People With Progressive Multiple Sclerosis Using Aerobic Exercise and Cognitive Rehabilitation

NACompletedINTERVENTIONAL
Enrollment

309

Participants

Timeline

Start Date

March 18, 2019

Primary Completion Date

October 30, 2022

Study Completion Date

February 3, 2023

Conditions
Multiple Sclerosis, Primary ProgressiveCognitive Impairment
Interventions
OTHER

Cognitive Rehabilitation

"RehaCom software~Information processing speed and attention modules"

OTHER

Sham Exercise

Sets of balance and stretching exercises

OTHER

Sham Cognitive Rehabilitation

"Kompozer software~24 session module consisting of basic internet searches"

OTHER

Aerobic Exercise

"Recumbent NuStep Bike~Aerobic cycling"

Trial Locations (1)

M4N3M5

Sunnybrook Health Science Center, Toronto

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

University of Florence

OTHER

collaborator

Fondazione Italiana Sclerosi Multipla

OTHER

collaborator

University College, London

OTHER

collaborator

Kessler Foundation

OTHER

collaborator

University of Alabama at Birmingham

OTHER

collaborator

University of Southern Denmark

OTHER

collaborator

Hasselt University

OTHER

collaborator

University of Plymouth

OTHER

collaborator

Universita degli Studi di Genova

OTHER

collaborator

Unity Health Toronto

OTHER

collaborator

Ospedale San Raffaele

OTHER

lead

Sunnybrook Health Sciences Centre

OTHER