A Study Combining Personalized Neoantigen-based Dendritic Cell Vaccine With Microwave Ablation for the Treatment of Hepatocellular Carcinoma

PHASE1UnknownINTERVENTIONAL
Enrollment

24

Participants

Timeline

Start Date

October 15, 2018

Primary Completion Date

October 15, 2020

Study Completion Date

December 15, 2020

Conditions
Hepatocellular CarcinomaLiver Cancer, Adult
Interventions
BIOLOGICAL

Neoantigen Vaccines

HCC (3cm≤D ≤5 cm, fewer than three tumors) patients were treated with Microwave Ablation and 7 courses of neoantigen-based DC vaccines.The first neoantigen-based DC vaccine injection will take place up to 30 days following the completion of Microwave Ablation. The day of the first vaccine injection will be referred to as Day 1.The schedule of vaccination is Day 1, Day 8, Day 15, Day 22, Day 50, Day78, Day106.

PROCEDURE

Microwave Ablation

ALL the HCC patients will be treated by Microwave Ablation.

Trial Locations (1)

100853

RECRUITING

Chinese PLA General Hospital, Beijing

Sponsors
All Listed Sponsors
collaborator

Likang Life Sciences Holdings Limited

UNKNOWN

lead

Chinese PLA General Hospital

OTHER