Transcranial Magnetic Stimulation for Attention Deficit/Hyperactivity Disorder (ADHD)

NACompletedINTERVENTIONAL
Enrollment

32

Participants

Timeline

Start Date

January 31, 2017

Primary Completion Date

March 31, 2019

Study Completion Date

January 1, 2020

Conditions
Attention Deficit Disorder With Hyperactivity (ADHD)
Interventions
DEVICE

Transcranial Magnetic Stimulation (TMS)

A MagPro R30 (Magventure, Inc., Copenhagen, Denmark) device with a Cool-B65 A/P figure 8 coil will be used to deliver TMS. This coil has an active side and a sham side, and can be used to perform double-blinded studies. TMS will be administered at 10 Hertz (Hz) with an intensity of 120% of patient resting motor threshold. Stimulation will be delivered to the left dorsolateral prefrontal cortex using 20 sec cycles (i.e., 5 sec train with 15 sec inter train interval). Subjects will receive 80 trains per session for a total of 4000 pulses per session (\~26 min sessions). Twenty sessions will be completed on sequential weekdays (5 days per week for 4 weeks).

DEVICE

Sham Transcranial Magnetic Stimulation (Sham TMS)

A MagPro R30 (Magventure, Inc., Copenhagen, Denmark) device with a Cool-B65 A/P figure 8 coil will be used to deliver TMS. This coil has an active side and a sham side, and can be used to perform double-blinded studies. For sham stimulation, the sham side of the coil is positioned toward the participant's scalp. The sham coil is designed to mimic the appearance and sound of active TMS stimulation, but is equipped with a magnetic shield that reduces the strength of the field by approximately 80%. This reduction in field strength ensures that no neural stimulation occurs. Twenty sessions will be completed on sequential weekdays (5 days per week for 4 weeks).

Trial Locations (1)

19104

University of Pennsylvania, Philadelphia

All Listed Sponsors
lead

University of Pennsylvania

OTHER

NCT03663179 - Transcranial Magnetic Stimulation for Attention Deficit/Hyperactivity Disorder (ADHD) | Biotech Hunter | Biotech Hunter