NCT03661645View on ClinicalTrials.gov

Post-operative Methylprednisolone Taper Course for Orthopedic Surgery

PHASE4Enrolling by invitationINTERVENTIONAL
Enrollment

500

Participants

Timeline

Start Date

September 7, 2018

Primary Completion Date

January 31, 2029

Study Completion Date

January 31, 2029

Conditions
Orthopedic Surgeries
Interventions
DRUG

10 mg IV dexamethasone & 6 day oral methylprednisolone taper

"Drug: 6-day oral methylprednisolone (glucocorticoid) taper course The oral methylprednisolone taper course will begin on the day of surgery and will include 24mg on day 1, 20mg on day 2, 16mg on day 3, 12mg on day 4, 8mg on day 5, and 4mg on day.~Drug:10 mg intravenous (IV) dexamethasone"

OTHER

10 mg IV dexamethasone

Drug:10 mg intravenous (IV) dexamethasone

Trial Locations (3)

30322

Emory Clinic A, Clifton Road Clinic, Atlanta

30329

21 Ortho Lane, Atlanta

Emory Healthcare Orthopaedics and Spine Center, Atlanta

All Listed Sponsors
lead

Emory University

OTHER