Dose Individualization of Pemetrexed - IMPROVE-I

PHASE4CompletedINTERVENTIONAL
Enrollment

6

Participants

Timeline

Start Date

February 1, 2019

Primary Completion Date

December 1, 2023

Study Completion Date

December 29, 2023

Conditions
Non Small Cell Lung CancerMesothelioma
Interventions
DRUG

Pemetrexed + oral folinic acid rescue

3+3 dose escalation study of pemetrexed in patients with impaired renal function in combination with roal folinic acid rescue

Trial Locations (6)

Unknown

Jeroen Bosch Hospital, 's-Hertogenbosch

Antoni van Leeuwenhoek, Amsterdam

Catharina hospital, Eindhoven

Maastricht University Medical centre, Maastricht

Radboud university medical centre, Nijmegen

Erasmus University Medical Centre, Rotterdam

All Listed Sponsors
collaborator

ZonMw: The Netherlands Organisation for Health Research and Development

OTHER

lead

Radboud University Medical Center

OTHER

NCT03656549 - Dose Individualization of Pemetrexed - IMPROVE-I | Biotech Hunter | Biotech Hunter