Tranexamic Acid in Total Knee Replacement

NACompletedINTERVENTIONAL
Enrollment

180

Participants

Timeline

Start Date

October 1, 2015

Primary Completion Date

March 31, 2017

Study Completion Date

March 31, 2017

Conditions
Osteo Arthritis Knee
Interventions
DRUG

Tranexamic Acid

1 dose of IV TXA (15mg/kg) in 100-ml normal saline, 10 minutes before incision, administered during the induction of the anesthesia

DRUG

Tranexamic Acid

1 dose of IV TXA (15mg/kg) in 100-ml normal saline, 10 minutes before incision and an additional dose of IV TXA (15mg/kg) in 100-ml normal saline 3 hours after skin incision

DRUG

Tranexamic Acid

1 dose of IV TXA (15mg/kg) in 100-ml normal saline, before incision and two additional doses of IV TXA (15mg/kg) in 100-ml normal saline 3 and 6 hours after skin incision respectivel

All Listed Sponsors
lead

Democritus University of Thrace

OTHER

NCT03656445 - Tranexamic Acid in Total Knee Replacement | Biotech Hunter | Biotech Hunter