Perioperative Fluid Therapy Optimization in Spinal Surgery

NACompletedINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

August 21, 2018

Primary Completion Date

April 30, 2020

Study Completion Date

July 30, 2020

Conditions
HypovolemiaHypervolemia
Interventions
PROCEDURE

Standard care group

Patient will receive 2 ml/kg/hour of crystalloids (Ringerfundin BBraun) intraoperatively. Fluid boluses will be used according to anesthesiologists decision (timing and amount of fluids). In case of drop of mean arterial pressure (MAP) below 65 mmHg norepinephrine will be started (with initial bolus of 5 - 10 ug).

PROCEDURE

Noninvasive monitoring group

Patient will receive 2 ml/kg/hour of crystalloids (Ringerfundin BBraun) intraoperatively. In case of hypotension (defined as a mean arterial pressure below 65 mmHg), the intervention will be led according to a protocol based on cardiac index, systemic vascular resitance and stroke volume variation (SVV) values (ClearSight, Edwards).

Trial Locations (1)

50005

University Hospital Hradec Kralove, Hradec Králové

All Listed Sponsors
lead

University Hospital Hradec Kralove

OTHER

NCT03644654 - Perioperative Fluid Therapy Optimization in Spinal Surgery | Biotech Hunter | Biotech Hunter