Clinical Outcome of Delayed or Standard Prograf Together With Induction Therapy Followed by Conversion to Advagraf in Donation After Cardiac (or Circulatory) Death (DCD) Kidney Transplant Recipients

PHASE4CompletedINTERVENTIONAL
Enrollment

284

Participants

Timeline

Start Date

October 21, 2018

Primary Completion Date

July 15, 2022

Study Completion Date

July 15, 2022

Conditions
Kidney Transplant
Interventions
DRUG

Tacrolimus immediate-release formulation

oral

DRUG

Tacrolimus prolonged-release formulation

oral

DRUG

Induction therapy

All participants will receive induction therapy. The dosage and administration of induction immunotherapy will be a single kind of drug determined by the investigator.

DRUG

Mycophenolic acid drugs

All participants will receive mycophenolic acid drugs in combination with corticosteroids. The dosage and administration of mycophenolic acid will be determined by the investigator.

DRUG

Corticosteroids

All participants will receive corticosteroids in combination with mycophenolic acid drugs. The dosage and administration of corticosteroids will be determined by the investigator.

Trial Locations (14)

Unknown

Site CN08608, Beijing

Site CN08619, Beijing

Site CN08609, Changsha

Site CN08604, Guangzhou

Site CN08614, Hangzhou

Site CN08617, Hangzhou

Site CN08610, Nanjing

Site CN08618, Nanjing

Site CN08612, Shanghai

Site CN08603, Tianjin

Site CN08621, Wenzhou

Site CN08602, Wuhan

Site CN08613, Wuhan

Site CN08605, Xi'an

All Listed Sponsors
lead

Astellas Pharma China, Inc.

INDUSTRY

NCT03644485 - Clinical Outcome of Delayed or Standard Prograf Together With Induction Therapy Followed by Conversion to Advagraf in Donation After Cardiac (or Circulatory) Death (DCD) Kidney Transplant Recipients | Biotech Hunter | Biotech Hunter