Narcotic Free TIVA and Incidence of Unacceptable Movements Under Anesthesia During ACDF Surgery

PHASE4CompletedINTERVENTIONAL
Enrollment

32

Participants

Timeline

Start Date

July 15, 2018

Primary Completion Date

July 5, 2022

Study Completion Date

July 5, 2022

Conditions
Anterior Cervical Discectomy and Fusion (ACDF)
Interventions
DRUG

Remifentanil

Remifentanil infusion of 0.05 to 0.2 mcg/kg/minute started just prior to induction and stopped at emergence from anesthesia.

DRUG

Ketamine

Ketamine infusion of 2 mcg/kg/minute will be started at induction. It will be stopped at the beginning of the emergence from anesthesia, roughly 45 minutes from extubation.

DRUG

Dexmedetomidine

dexmedetomidine bolus of 0.5 mcg/kg over 10 minutes starting 5 minutes prior to induction followed by an infusion of 0.2-0.7 mcg/kg/hour that will be stopped with the start of closing the surgical wound.

Trial Locations (1)

72205

University of Arkansas for Medical Sciences, Little Rock

All Listed Sponsors
lead

University of Arkansas

OTHER

NCT03643796 - Narcotic Free TIVA and Incidence of Unacceptable Movements Under Anesthesia During ACDF Surgery | Biotech Hunter | Biotech Hunter