Hyponatremia Study (Delayed Hyponatremia After Pituitary Surgery)

NACompletedINTERVENTIONAL
Enrollment

300

Participants

Timeline

Start Date

June 2, 2016

Primary Completion Date

July 22, 2024

Study Completion Date

July 22, 2024

Conditions
HyponatremiaHyponatremicPituitary TumorPituitarySurgery
Interventions
OTHER

Fluid Restricted Group

"Patients will be started on a weight-based intravenous fluid replacement with D5 ½ NS on POD 0 (75 cc/hr for patients \< 70kg, 100 cc/hr for patients 70-100kg, and 125 cc/hr for patients \>100kg). Patients will be allowed to drink water freely after surgery on POD #0. Fluids will be stopped at 8am on POD 1 and patients will be started on a moderate fluid restriction on POD #3 based on their weight (1000 cc/24 hours for patients who weigh \<=100 kg and 1200 cc/24 hours for patients who weigh \> 100kg). Prior to initiation of a fluid restriction all of the following criteria have to be met:~1. Serum Na level must be \< 145 mEq/l~2. Patient should be taking fluids by mouth~3. Patient should not have evidence of DI (as determined by endocrine team following patient) If a patient in Fluid Restricted group develops DI, the fluid restriction will be stopped/not initiated."

Trial Locations (1)

63110

Barnes Jewish Hospital, St Louis

All Listed Sponsors
lead

Washington University School of Medicine

OTHER

NCT03636568 - Hyponatremia Study (Delayed Hyponatremia After Pituitary Surgery) | Biotech Hunter | Biotech Hunter