A Study of the Efficacy and Safety of Bevacizumab in Chinese Women With Newly Diagnosed, Previously Untreated Stage III or Stage IV Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

PHASE3CompletedINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

August 15, 2018

Primary Completion Date

May 26, 2021

Study Completion Date

May 11, 2023

Conditions
Ovarian CancerFallopian Tube CancerPrimary Peritoneal Cancer
Interventions
DRUG

Paclitaxel

175 mg/m\^2 IV infusion on Day 1 of each 21-day cycle.

DRUG

Bevacizumab

15 mg/kg IV infusion on Day 1 of each 21-day cycle.

DRUG

Carboplatin

Area Under the Curve (AUC) of 6 mg/ml/min on Day 1 of each 21-day cycle.

DRUG

Placebo

Placebo matched to bevacizumab IV infusion on Day 1 of each 21-day cycle.

Trial Locations (16)

100006

Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing

130021

the First Hospital of Jilin University, Changchun

132013

Jilin Cancer Hospital, Changchun

150081

Harbin Medical University Cancer Hospital, Harbin

200120

Fudan University Shanghai Cancer Center, Shanghai

210008

Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School, Nanjing

226361

Nantong Tumor Hospital, Nantong

300052

Tianjin Medical University General Hospital, Tianjin

310022

Zhejiang Cancer Hospital; Zhejiang Cancer Hospital cancer department, Hangzhou

350014

Fujian Cancer Hospital, Fuzhou

410008

Xiangya Hospital Central South University, Changsha

450008

Henan Cancer Hospital, Zhengzhou

510663

Sun Yet-sen University Cancer Center, Guangzhou

530021

Guangxi Cancer Hospital of Guangxi Medical University, Nanning

610066

West China Second University Hospital, Chengdu

710061

First Affiliated Hospital of Medical College of Xi'an Jiaotong University, Xi'an

All Listed Sponsors
lead

Hoffmann-La Roche

INDUSTRY

NCT03635489 - A Study of the Efficacy and Safety of Bevacizumab in Chinese Women With Newly Diagnosed, Previously Untreated Stage III or Stage IV Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer | Biotech Hunter | Biotech Hunter