A Two Chemoprophylaxis Approaches After Phacoemulsification Surgery

PHASE4CompletedINTERVENTIONAL
Enrollment

1,000

Participants

Timeline

Start Date

October 1, 2016

Primary Completion Date

February 1, 2018

Study Completion Date

February 1, 2018

Conditions
Endophthalmitis Postoperative
Interventions
DRUG

Moxifloxacin hydrochloride 0.5% eye drops

were prescribed four times a day for 1-month postoperatively

DRUG

Dexamethasone 0.1% eye drops

were prescribed four times a day for 1-month postoperatively

DRUG

Intracameral Moxifloxacin 0.1%

"Auromox (0.5%): is a sterile clear yellow pale colored preservative free isotonic ophthalmic solution with pH 6.0 to 7.5 and osmolarity 620 -320 milliosmol ( mOsm).The sterile Auromox vial contains 1cc Moxifloxacin hydrochloride 5.45 mg equivalent to 5mg of Moxifloxacin. This product is manufactured by Aurolab an Indian pharmaceutical company. Auromox is available in many countries including Iraq.~Each vial enough for 15 different patients by using a sterile needle and 5cc syringe. By the sterile hand's, the surgeon draws the whole 1cc of Moxifloxacin 0.5% and diluted with 4 cc of balanced salt solution (BSS) to get 5 mg in 5 cc (0.1%) then draw 0.2 cc for each patient."

DRUG

Subconjunctival Triamcinolone acetonide 4 mg /0.4 ml

"Aurocort is a preservative-free Triamcinolone acetonide (40 mg /1cc), with along acting depot preparation of triamcinolone in 1cc vial also the product of Aurolab company and commercially available in our country.~The whole 1cc had been drawn and diluted with 3cc of BSS and SC injection of 4 mg in 0.4 cc of Triamcinolone was given (as a final step in the surgery) 6mm from the limbus usually an inferotemporal site that is easily accessible and the plaque that formed will be not visible within palpebral fissure"

All Listed Sponsors
collaborator

Al-Kindy College of Medicine

OTHER

lead

Suzan A Rattan

OTHER

NCT03634852 - A Two Chemoprophylaxis Approaches After Phacoemulsification Surgery | Biotech Hunter | Biotech Hunter