Comparison Between Different Ventilator Hyperinflation Maneuvers

NACompletedINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

March 18, 2017

Primary Completion Date

September 30, 2017

Study Completion Date

May 23, 2018

Conditions
Infections, RespiratoryVentilator Associated Pneumonia
Interventions
OTHER

VCV20

controlled volume ventilation mode under constant flow of 20 Lpm. The inspired volume was progressively increased until the Pmax reached 40cmH2O.

OTHER

VCV40

volume controlled ventilation mode under constant flow of 40 Lpm. The inspired volume was progressively increased until the Pmax reached 40cmH2O.

OTHER

PCV

controlled ventilation mode, 1 second inspiratory time. The inspiratory pressure was increased every 5 cmH2O, until reaching the maximum pressure of 40 cmH2O.

OTHER

PCV+Tins

controlled ventilation and inspiratory pressure was increased every 5 cmH2O until the maximum pressure was 40 cmH2O. The inspiratory time was gradually increased until the inspiratory flow reached the baseline. Concomitantly, the respiratory rate was decreased to allow the expiratory flow also to reach the baseline, to avoid self-PEEP.

OTHER

PSV

ventilatory mode with pressure support, with progressive increases of 5 cmH2O at inspiratory pressure, until reaching Pmax of 40 cmH2O. The expiratory sensitivity was adjusted by 25% for all patients.

Trial Locations (1)

28015150

Luciano M Chicayban, Campos dos Goytacazes

All Listed Sponsors
lead

Brazilian Institute of Higher Education of Censa

OTHER

NCT03631342 - Comparison Between Different Ventilator Hyperinflation Maneuvers | Biotech Hunter | Biotech Hunter