Effects of 20,000 EU of Clinical Center Reference Endotoxin (CCRE) Versus Placebo(ENDOHEART)

PHASE1CompletedINTERVENTIONAL
Enrollment

15

Participants

Timeline

Start Date

October 17, 2018

Primary Completion Date

September 17, 2019

Study Completion Date

September 17, 2019

Conditions
Healthy
Interventions
DRUG

Clinical Center Reference Endotoxin (CCRE)

subjects will undergo an exposure to inhaled endotoxin through a nebulizer for approximately 10 minutes.

DRUG

Normal saline

subjects will undergo an exposure to inhaled normal saline through a nebulizer for approximately 10 minutes

Trial Locations (1)

27599

EPA Human Studies Facility, Chapel Hill

All Listed Sponsors
collaborator

Environmental Protection Agency (EPA)

FED

collaborator

RTI International

OTHER

collaborator

United States Department of Defense

FED

lead

University of North Carolina, Chapel Hill

OTHER

NCT03623022 - Effects of 20,000 EU of Clinical Center Reference Endotoxin (CCRE) Versus Placebo(ENDOHEART) | Biotech Hunter | Biotech Hunter