Colistin-rifampin Combination and Colistin Monotherapy in Extensively Drug-resistant Acinetobacter Baumannii

NACompletedINTERVENTIONAL
Enrollment

9

Participants

Timeline

Start Date

October 27, 2016

Primary Completion Date

September 24, 2017

Study Completion Date

June 21, 2018

Conditions
ColistinRifampinAcinetobacter Infections
Interventions
DRUG

colistin and rifampin combination therapy

Colistin (100 mg, colistin sodium methanesulfonate, SCD Pharm., Seoul, Korea) will be intravenously administered with 100 mL of normal saline with 8 hours interval. Rifampin (600 mg, rifampin, Yuhan, Seoul, Korea) will be orally administered daily. Treatment should be maintained daily administration for at least 7 days and up to 28 days. Duration of antibiotics treatment will be determined through discussion by pulmonology and infection specialist.

DRUG

colistin monotherapy

. Colistin (100 mg, colistin sodium methanesulfonate, SCD Pharm., Seoul, Korea) will be intravenously administered with 100 mL of normal saline with 8 hours interval. Treatment should be maintained daily administration for at least 7 days and up to 28 days. Duration of antibiotics treatment wil be determined through discussion by pulmonology and infection specialist .

All Listed Sponsors
lead

Gangnam Severance Hospital

OTHER

NCT03622918 - Colistin-rifampin Combination and Colistin Monotherapy in Extensively Drug-resistant Acinetobacter Baumannii | Biotech Hunter | Biotech Hunter