NCT03620773View on ClinicalTrials.gov

Impact of Metabolic Surgery on Pancreatic, Renal and Cardiovascular Health in Youth With Type 2 Diabetes

PHASE1/PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

October 1, 2018

Primary Completion Date

October 1, 2024

Study Completion Date

October 1, 2024

Conditions
Type 2 Diabetes MellitusObesityBariatric Surgery CandidateNephropathyDiabetic Kidney DiseaseDiabetes Mellitus, Type 2Diabetes MellitusDiabetes ComplicationsWeight LossDiabetic NephropathiesAdolescent ObesityPediatric Obesity
Interventions
DRUG

Aminohippurate Sodium Inj 20%

Diagnostic aid/agent used to measure effective renal plasma flow (ERPF)

DRUG

Iohexol Inj 300 mg/mL

Diagnostic aid/agent used to measure glomerular filtration rate (GFR)

PROCEDURE

Vertical Sleeve Gastrectomy

Participants will undergo vertical sleeve gastrectomy surgery, a laparoscopic bariatric surgery procedure designed for weight loss in obese patients

PROCEDURE

Renal Biopsy

Minimally invasive outpatient procedure in interventional radiology to obtain renal tissue cores.

Trial Locations (1)

80045

Children's Hospital Colorado, Aurora

All Listed Sponsors
lead

University of Colorado, Denver

OTHER