NCT03615742View on ClinicalTrials.gov

Diesel Exhaust Induces Glucocorticoid Resistance

PHASE4RecruitingINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

December 1, 2018

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2025

Conditions
Exposure to PollutionGlucocorticoid Resistance
Interventions
OTHER

Placebo

Inhalation of air through a Turbuhaler that contains no medication, as a control.

DRUG

Budesonide

1.6mg of budesonide from a Turbuhaler.

OTHER

Filtered Air

Exposure to HEPA filtered air, as a control.

OTHER

Diesel Exhaust

Diesel exhaust standardized to 300µg/m³ of particulate matter with a diameter of 2.5 micrometers or less (PM2.5).

Trial Locations (1)

V5Z1M9

RECRUITING

University of British Columbia, Vancouver

All Listed Sponsors
collaborator

Canadian Institutes of Health Research (CIHR)

OTHER_GOV

collaborator

AllerGen NCE Inc.

INDUSTRY

lead

University of British Columbia

OTHER