Clinic Trial to Evaluate the Safety and Immunogenicity by Different Sequential Schedules of bOPV and IPV

PHASE3CompletedINTERVENTIONAL
Enrollment

1,200

Participants

Timeline

Start Date

September 15, 2015

Primary Completion Date

August 31, 2016

Study Completion Date

August 31, 2016

Conditions
Poliomyelitis
Interventions
BIOLOGICAL

1-dose cIPV + 2-doses bOPV (Candy)

Health subjects received 1-dose cIPV intramuscularly in the centre of anterolateral thigh followed by 2-doses bOPV(Candy) through mouth at 0, 28, 56 days schedule.

BIOLOGICAL

1-dose sIPV + 2-doses bOPV (Candy)

Health subjects received 1-dose sIPV intramuscularly in the centre of anterolateral thigh followed by 2-doses bOPV(Candy) through mouth at 0, 28, 56 days schedule.

BIOLOGICAL

2-doses cIPV + 1-dose bOPV (Candy)

Health subjects received 2-doses cIPV intramuscularly in the centre of anterolateral thigh followed by 1-dose bOPV(Candy) through mouth at 0, 28, 56 days schedule.

BIOLOGICAL

2-doses sIPV + 1-dose bOPV (Candy)

Health subjects received 2-doses sIPV intramuscularly in the centre of anterolateral thigh followed by 1-dose bOPV(Candy) through mouth at 0, 28, 56 days schedule.

BIOLOGICAL

2-doses cIPV + 1-dose tOPV (Candy)

Health subjects received 2-doses cIPV intramuscularly in the centre of anterolateral thigh followed by 1-dose tOPV(Candy) through mouth at 0, 28, 56 days schedule.

BIOLOGICAL

2-doses sIPV + 1-dose tOPV (Candy)

Health subjects received 2-doses sIPV intramuscularly in the centre of anterolateral thigh followed by 1-dose tOPV(Candy) through mouth at 0, 28, 56 days schedule.

BIOLOGICAL

1-dose cIPV + 2-doses bOPV (Liquid)

Health subjects received 1-dose cIPV intramuscularly in the centre of anterolateral thigh followed by 2-doses bOPV(Liquid) through mouth at 0, 28, 56 days schedule.

BIOLOGICAL

1-dose sIPV + 2-doses bOPV (Liquid)

Health subjects received 1-dose sIPV intramuscularly in the centre of anterolateral thigh followed by 2-doses bOPV(Liquid) through mouth at 0, 28, 56 days schedule.

BIOLOGICAL

2-doses cIPV + 1-dose bOPV (Liquid)

Health subjects received 2-doses cIPV intramuscularly in the centre of anterolateral thigh followed by 1-dose bOPV(Liquid) through mouth at 0, 28, 56 days schedule.

BIOLOGICAL

2-doses sIPV + 1-dose bOPV (Liquid)

Health subjects received 2-doses sIPV intramuscularly in the centre of anterolateral thigh followed by 1-dose bOPV(Liquid) through mouth at 0, 28, 56 days schedule.

BIOLOGICAL

2-doses cIPV + 1-dose tOPV (Liquid)

Health subjects received 2-doses cIPV intramuscularly in the centre of anterolateral thigh followed by 1-dose tOPV(Liquid) through mouth at 0, 28, 56 days schedule.

BIOLOGICAL

2-doses sIPV + 1-dose tOPV (Liquid)

Health subjects received 2-doses sIPV intramuscularly in the centre of anterolateral thigh followed by 1-dose tOPV(Liquid) through mouth at 0, 28, 56 days schedule.

Trial Locations (1)

530028

Guangxi Provincial Center for Diseases Control and Prevention, Nanning

All Listed Sponsors
collaborator

Guangxi Center for Disease Control and Prevention

OTHER_GOV

lead

Institute of Medical Biology, Chinese Academy of Medical Sciences

OTHER

NCT03614702 - Clinic Trial to Evaluate the Safety and Immunogenicity by Different Sequential Schedules of bOPV and IPV | Biotech Hunter | Biotech Hunter