To Evaluate the Safety, Tolerability, and Pharmacokinetics Profile in Healthy Chinese Volunteers of TG-2349

PHASE1CompletedINTERVENTIONAL
Enrollment

64

Participants

Timeline

Start Date

April 27, 2017

Primary Completion Date

August 31, 2017

Study Completion Date

August 31, 2017

Conditions
Healthy Chinese Volunteers
Interventions
DRUG

Furaprevir capsule (SAD)

There are four doses in this part, 100 mg, 200 mg, 400 mg, and 600 mg. Each subject will receive the sample once by oral administration.

DRUG

Furaprevir capsule (MAD)

There are three doses in this part, 200 mg, 400 mg, and 600 mg. Each subject will be allocated into one dosing regimen and receive the sample once daily for 5 consecutive days by oral administration.

DRUG

Placebo (SAD)

Each subject will receive the sample once by oral administration.

DRUG

Placebo (MAD)

Each subject will be allocated into one dosing regimen and receive the sample once daily for 5 consecutive days by oral administration.

Trial Locations (1)

Unknown

Xiangya Hospital Central South University, Changsha

All Listed Sponsors
collaborator

R&G Pharma Studies Co.,Ltd.

INDUSTRY

lead

Dongguan HEC TaiGen Biopharmaceuticals Co., Ltd.

INDUSTRY

NCT03610867 - To Evaluate the Safety, Tolerability, and Pharmacokinetics Profile in Healthy Chinese Volunteers of TG-2349 | Biotech Hunter | Biotech Hunter