Efficacy and Safety of Rapid Titration Protocols of Lacosamide

PHASE4CompletedINTERVENTIONAL
Enrollment

75

Participants

Timeline

Start Date

August 3, 2018

Primary Completion Date

June 7, 2019

Study Completion Date

June 7, 2019

Conditions
Focal Epilepsy
Interventions
DRUG

Lacosamide - conventional titration

Administration of lacosamide by the following schedule, Initial: 50 mg PO BID Increase dose at weekly intervals by 50 mg PO BID; up to 200 mg BID

DRUG

Lacosamide - rapid titration 1

Administration of lacosamide by the following schedule, Initial: 100 mg PO BID Increase dose to 200 mg BID after one week

DRUG

Lacosamide - rapid titration 2

Administration of lacosamide by the following schedule, Initial: 50 mg PO BID Increase dose every two days by 50 mg PO BID; up to 200 mg BID

Trial Locations (1)

Unknown

Seoul National University Hospital, Seoul

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Dongsan Medical Center

OTHER

collaborator

Konkuk University

OTHER

lead

Seoul National University Hospital

OTHER