Study of Coronary Calcium Score as a Marker of Post-radiation Vascular Dysplasia in Adults Treated During Childhood for Cancer With Mediastinal Irradiation

NARecruitingINTERVENTIONAL
Enrollment

500

Participants

Timeline

Start Date

June 14, 2018

Primary Completion Date

September 30, 2028

Study Completion Date

September 30, 2028

Conditions
Childhood Cancer
Interventions
OTHER

Coronal calcium score measurement

"A medical interview with clinical examination by a cardiologist for screening cardiovascular risk factors, including smoking, and looking for symptoms of heart disease as part of routine care.~In accordance with routine care, a fasting and fasting blood test will be performed performed on exam day at Bichat Hospital or at another time, close to the patient's home according to his availability. The biological blood test will include the measurement of plasma triglyceride concentrations, total cholesterol and its HDL and LDL fractions, blood glucose, glycated hemoglobin and serum creatinine with estimated glomerular filtration rate according to the CKD-EPI formula. Sample urinalysis will include measurement of creatinine, proteinuria, and microalbuminuria.~An electrocardiogram (ECG) rest, a cardiac ultrasound, a test and respiratory function tests (EFR) will be performed as part of routine care. Coronal calcium score measurement will be performed as part of the research."

Trial Locations (3)

94805

RECRUITING

Gustave Roussy, Villejuif

Unknown

RECRUITING

Hôpital Bichat, Paris

RECRUITING

Hôpital Trousseau, Paris

All Listed Sponsors
lead

Gustave Roussy, Cancer Campus, Grand Paris

OTHER