ONES Grant: CXCL10/CXCR3 Regulation of Ozone-Induced Epithelial Permeability

EARLY_PHASE1CompletedINTERVENTIONAL
Enrollment

14

Participants

Timeline

Start Date

August 16, 2019

Primary Completion Date

November 29, 2023

Study Completion Date

January 24, 2024

Conditions
Environmental and Genetic Factors on Lung Function
Interventions
DRUG

Ozone

Subjects will perform alternating 15 minutes rest with 15 minutes treadmill walk exercise periods for 135 minutes in while breathing Ozone (O3).

OTHER

Filtered Air

Subjects will perform alternating 15 minutes rest with 15 minutes treadmill walk exercise periods for 135 minutes in while breathing filtered air.

Trial Locations (1)

27705

Duke Asthma, Allergy, and Airway Center, Durham

All Listed Sponsors
lead

Robert Tighe, MD

OTHER

NCT03599206 - ONES Grant: CXCL10/CXCR3 Regulation of Ozone-Induced Epithelial Permeability | Biotech Hunter | Biotech Hunter