Early Prophylactic Donor Lymphocyte Infusion After Allo-HSCT for Patients With AML

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

124

Participants

Timeline

Start Date

September 7, 2020

Primary Completion Date

May 31, 2027

Study Completion Date

May 31, 2028

Conditions
Acute Myeloid Leukemia
Interventions
BIOLOGICAL

prophylactic donor lymphocyte infusion (DLI)

DLI will be collected from the donor by leukapheresis according to local standard procedures of each center. Cell product could be collected in one time or more, and administered fresh or after a frozen storage, according to each center's guidelines. A sufficient amount of T-cell dose should be collected to theoretically perform 3 DLI. DLI procedure will be performed according to local guidelines of each center.

Trial Locations (1)

13009

Institut Paoli-Calmettes, Marseille

All Listed Sponsors
lead

Institut Paoli-Calmettes

OTHER