BN Brachyury and Radiation in Chordoma

PHASE2CompletedINTERVENTIONAL
Enrollment

29

Participants

Timeline

Start Date

October 31, 2018

Primary Completion Date

December 10, 2021

Study Completion Date

January 25, 2022

Conditions
Chordoma
Interventions
BIOLOGICAL

BN-Brachyury plus radiation

MVA-BN-Brachyury injections will be given on day 0 and 14. FPV-Brachyury injection will be given on day 28, followed by radiation on days 42 through approximately day 70. FPV-Brachyury will then be given two weeks after radiation then every 6-12 weeks through 110 weeks after radiation is complete.

Trial Locations (5)

32224

Mayo Clinic, Florida, Jacksonville

63110

Washington University School of Medicine, St Louis

77030

MD Anderson Cancer Center, Houston

85054

Mayo Clinic, Arizona, Phoenix

02114

Massachusetts General Hospital, Cancer Center, Boston

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Bavarian Nordic

INDUSTRY

NCT03595228 - BN Brachyury and Radiation in Chordoma | Biotech Hunter | Biotech Hunter