Efficacy and Cost Analysis of Steroids in Treatment of Otitis Media With Effusion

PHASE4CompletedINTERVENTIONAL
Enrollment

160

Participants

Timeline

Start Date

September 5, 2018

Primary Completion Date

February 16, 2020

Study Completion Date

March 18, 2020

Conditions
Otitis Media With Effusion
Interventions
DRUG

Mometasone 50 Mcg/Inh Nasal Spray

One spray in each nostril once daily for one month

DRUG

Antibiotics + Antihistamine (levocetirizine) + Nasal decongestants (Oxymetazoline 0.025%)

Children in this group will be treated with antiboitics (syp cefpodoxime) at 10 mg/kg/day in two divided dose for a week, plus antihistamine and nasal decongestants. Oral levocetirizine (Syrup levocet 2.5 mg/5ml) 1.25 mg once daily for age up to six years, 2.5 mg once daily for elder children for a month, plus oxymetazoline (Nasivion) 0.025%, 4 drops twice daily for two weeks

DRUG

Steroid Drug (prednisolone)

This group will be treated with steroid drugs. Oral prednisolone, 1 mg/kg body weight daily in two divided dose for 1 week followed by half mg/kg/day in two divided dose for next one week.

Trial Locations (1)

32500

Lumbini Medical College, Tānsen

Sponsors
All Listed Sponsors
lead

Lumbini Medical College

OTHER