567
Participants
Start Date
May 1, 2018
Primary Completion Date
August 31, 2023
Study Completion Date
August 31, 2023
Transjugular intrahepatic portosystemic shunt
"Covered stents will be used, that will be dilated to 8 mm. The aim will be to reduce the portacaval pressure gradient (PPG) below to 25-75% of baseline. Not paralleled TIPS or over-dilatation are allowed.~Embolisation, either with coils or bucrylate, can be performed, if it is felt necessary, especially in patients where portography shows the filling of big portosystemic collaterals feeding the varices.~After TIPS, anticoagulation will not be used as a rule, but is allowed if the attending physician thinks that it is warranted.~Measurement of portacaval pressure gradient will be done immediate after TIPS, then repeated 1-3 days and at 1 month after the procedure.~A TIPS revision will be performed once shunt dysfunction is suspected."
Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an
Air Force Military Medical University, China
OTHER