Dynamic Monitor of Portacaval Pressure Gradient

CompletedOBSERVATIONAL
Enrollment

567

Participants

Timeline

Start Date

May 1, 2018

Primary Completion Date

August 31, 2023

Study Completion Date

August 31, 2023

Conditions
Liver Cirrhosis
Interventions
PROCEDURE

Transjugular intrahepatic portosystemic shunt

"Covered stents will be used, that will be dilated to 8 mm. The aim will be to reduce the portacaval pressure gradient (PPG) below to 25-75% of baseline. Not paralleled TIPS or over-dilatation are allowed.~Embolisation, either with coils or bucrylate, can be performed, if it is felt necessary, especially in patients where portography shows the filling of big portosystemic collaterals feeding the varices.~After TIPS, anticoagulation will not be used as a rule, but is allowed if the attending physician thinks that it is warranted.~Measurement of portacaval pressure gradient will be done immediate after TIPS, then repeated 1-3 days and at 1 month after the procedure.~A TIPS revision will be performed once shunt dysfunction is suspected."

Trial Locations (1)

710032

Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an

All Listed Sponsors
lead

Air Force Military Medical University, China

OTHER

NCT03590288 - Dynamic Monitor of Portacaval Pressure Gradient | Biotech Hunter | Biotech Hunter