Assessing Lung Inhomogeneity During Ventilation for Acute Hypoxemic Respiratory Failure

NACompletedINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

March 1, 2019

Primary Completion Date

March 31, 2021

Study Completion Date

August 31, 2021

Conditions
Acute Respiratory Distress SyndromeMechanical Ventilation Pressure HighHypoxemic Respiratory Failure
Interventions
DEVICE

Electrical Impedance Tomography

Electrical impedance tomography (EIT) is a new technique that enables real-time visualization of the distribution of ventilation at the bedside. This technique allows clinicians and investigators to immediately determine how applying higher or lower PEEP levels affect stress and strain in the lung. The investigators propose to apply this new technique to test a strategy for finding the optimal level of PEEP that prevents lung injury and improves outcomes in critically ill patients.

OTHER

ExPRESS-derived PEEP level

The ExPRESS algorithm is a traditional approach to selecting PEEP based on respiratory mechanics.

Trial Locations (1)

M5G 2N2

University Health Network, Toronto

All Listed Sponsors
lead

University Health Network, Toronto

OTHER

NCT03589482 - Assessing Lung Inhomogeneity During Ventilation for Acute Hypoxemic Respiratory Failure | Biotech Hunter | Biotech Hunter