AAVCAGsCD59 for the Treatment of Wet AMD

PHASE1CompletedINTERVENTIONAL
Enrollment

25

Participants

Timeline

Start Date

September 13, 2018

Primary Completion Date

January 29, 2020

Study Completion Date

January 18, 2022

Conditions
Wet Age-related Macular Degeneration
Interventions
DRUG

Intravitreal anti-VEGF

Intravitreal injection of anti-VEGF at Day 0 then monthly as needed

BIOLOGICAL

Intravitreal AAVCAGsCD59

An intravitreal injection of AAVCAGsCD59 will occur at Day 7 once

DRUG

Oral prednisolone

A 7 day tapering dose of oral prednisone will be taken at Day 30 by all patients

Trial Locations (2)

02114

Ophthalmic Consultants of Boston, Boston

01605

Vitreo-Retina Associates, Worcester

All Listed Sponsors
lead

Janssen Research & Development, LLC

INDUSTRY

NCT03585556 - AAVCAGsCD59 for the Treatment of Wet AMD | Biotech Hunter | Biotech Hunter