Treatment of Complicated Parapneumonic Effusion With Fibrinolytic Therapy Versus VATs Decortication

NACompletedINTERVENTIONAL
Enrollment

10

Participants

Timeline

Start Date

July 26, 2018

Primary Completion Date

February 2, 2020

Study Completion Date

February 2, 2020

Conditions
Parapneumonic EffusionEmpyema, PleuralCoagulopathy
Interventions
PROCEDURE

VATS Decortication

Surgical procedure to unroof all located collections of the pleural space through a chest wall incision

DRUG

Fibrinolytic Therapy

Instillation of DNAse and tPA together through patient's chest tube already in placed to break down complex fluid collection in the pleural space. DNAse and tPA are are administered together only i.e. are not mutually exclusive.

Trial Locations (1)

80204

Denver Health, Denver

All Listed Sponsors
lead

Denver Health and Hospital Authority

OTHER

NCT03583931 - Treatment of Complicated Parapneumonic Effusion With Fibrinolytic Therapy Versus VATs Decortication | Biotech Hunter | Biotech Hunter