Thrombolysis With rhPro-UK in 4.5-6 Hours After Acute Ischemic Stroke in a Double-blinded,Controlled Trial

PHASE3CompletedINTERVENTIONAL
Enrollment

149

Participants

Timeline

Start Date

August 10, 2018

Primary Completion Date

February 28, 2020

Study Completion Date

March 1, 2020

Conditions
Acute Ischaemic Stroke
Interventions
DRUG

Recombinant human urokinase

Patients receive rhPro-UK 35mg,15mg of which is given as a bolus within 3min followed by dlivery of the remaining 20 mg as a constant infusion over a period of 30 min.

DRUG

Aspirin

Aspirin 300mg is taken orally at the beginning of thrombolysis.

DRUG

rhPro-UK simulation agent

Patients receive rhPro-UK simulation agent 35mg,15mg of which is given as a bolus within 3min followed by dlivery of the remaining 20 mg as a constant infusion over a period of 30 min.

DRUG

Aspirin simulation agent

Aspirin simulation agent 300mg is taken orally at the beginning of thrombolysis.

Trial Locations (19)

Unknown

XuanWu Hospital, Capital Medical University, Beijing

Harrison International Peace Hospital, Hengshui

Tangshan Gongren Hospital, Tangshan

Baotou Central Hospital, Baotou

First Affiliated Hospital of Baotou Medical College, Baotou

Affiliated Hospital of Inner Mongolia Medical University, Hohhot

Inner Mongolia People's Hospital, Hohhot

Huai'an First People's Hospital, Huai'an

The Second People'Hospital of Huai'an, Huai'an

Zhongda Hospital Southeast University, Nanjing

The Affiliated Hospital of Xuzhou Medical University, Xuzhou

Xuzhou Central Hospital, Xuzhou

Jiangxi Pingxiang People's Hospital, Pingxiang

First Hospital of Jilin University, Changchun

Meihekou Central Hospital, Meihekou

Dalian Municipal Central Hospital, Dalian

Shenyang Military Region General Hospital, Shenyang

The First People's Hospital of Shenyang, Shenyang

Luoyang Central Hospital, Luoyang

All Listed Sponsors
lead

Tasly Biopharmaceuticals Co., Ltd.

INDUSTRY

NCT03578822 - Thrombolysis With rhPro-UK in 4.5-6 Hours After Acute Ischemic Stroke in a Double-blinded,Controlled Trial | Biotech Hunter | Biotech Hunter