Utility of EUS-guided Microbiopsies in Pancreatic Cystic Lesions

NACompletedINTERVENTIONAL
Enrollment

101

Participants

Timeline

Start Date

February 1, 2018

Primary Completion Date

August 31, 2019

Study Completion Date

August 31, 2019

Conditions
Pancreatic CystIPMNMucinous CystPancreatic Adenocarcinoma
Interventions
DEVICE

EUS-guided microbiopsy

Use of EUS-guided through-the-needle microbiopsy forceps for obtainment of tissue from the wall of the cystic lesion

DIAGNOSTIC_TEST

Next Generation Sequencing

Prevalence of genetic mutations in known cancer-associated genes in the microbiopsy tissue examined using the Ion AmpliSeq Cancer Hotspot Panel v2 (Life Technologies, Carlsbad, USA). The multigene panel explores selected regions of 50 cancer-associated genes, among others KRAS, GNAS, CDKN2A and SMAD4 genes.

Trial Locations (1)

2730

Gastro Unit, Division of Endoscopy, Herlev

All Listed Sponsors
collaborator

Rigshospitalet, Denmark

OTHER

lead

Herlev Hospital

OTHER

NCT03578445 - Utility of EUS-guided Microbiopsies in Pancreatic Cystic Lesions | Biotech Hunter | Biotech Hunter