3,600
Participants
Start Date
December 10, 2019
Primary Completion Date
December 31, 2027
Study Completion Date
December 31, 2028
Liberal phosphate target
All phosphate-lowering medications in use at baseline will be discontinued. Phosphate-lowering medications will be prescribed only if serum phosphate concentration exceeds 2.50 mmol/L. The choice and dosages of phosphate-lowering medications will be at the discretion of treating physicians and/or participants.
Intensive phosphate target
This will be achieved by prescribing phosphate-lowering medications aimed to intensively lower serum phosphate concentration towards normal level (≤1.50 mmol/L). The choice and dosages of phosphate-lowering medications will be at the discretion of treating physicians and/or participants.
ACTIVE_NOT_RECRUITING
Royal Prince Alfred Hosptial, Camperdown
ACTIVE_NOT_RECRUITING
Royal North Shore Hospital, Saint Leonards
ACTIVE_NOT_RECRUITING
Western Sydney Renal Service, Westmead
ACTIVE_NOT_RECRUITING
St George Hospital, Kogarah
ACTIVE_NOT_RECRUITING
Wollongong Hospital, Wollongong
ACTIVE_NOT_RECRUITING
Nepean Hospital, Kingswood
ACTIVE_NOT_RECRUITING
Royal Melbourne Hospital, Melbourne
ACTIVE_NOT_RECRUITING
St Vincent's Hospital Melbourne, Melbourne
ACTIVE_NOT_RECRUITING
Austin Health, Heidelberg
ACTIVE_NOT_RECRUITING
Latrobe Regional Hospital, Traralgon
ACTIVE_NOT_RECRUITING
Royal Brisbane and Women's Hospital, Brisbane
ACTIVE_NOT_RECRUITING
Princess Alexandra Hospital, Brisbane
ACTIVE_NOT_RECRUITING
Logan Hospital, Meadowbrook
ACTIVE_NOT_RECRUITING
Gold Coast University Hospital, Southport
ACTIVE_NOT_RECRUITING
Sunshine Coast University Hospital, Birtinya
ACTIVE_NOT_RECRUITING
Fraser Coast Renal Service, Hervey Bay
ACTIVE_NOT_RECRUITING
Bundaberg Hospital, Bundaberg
ACTIVE_NOT_RECRUITING
Mackay Hospital, Mackay
ACTIVE_NOT_RECRUITING
Townsville University Hospital, Townsville
ACTIVE_NOT_RECRUITING
Cairns Hospital, Cairns
ACTIVE_NOT_RECRUITING
Central and Northern Adelaide Renal and Transplant Service, Adelaide
ACTIVE_NOT_RECRUITING
Flinders Medical Centre, Bedford Park
ACTIVE_NOT_RECRUITING
Armadale Hospital, Armadale
RECRUITING
Ramathibodi Hospital, Bangkok
RECRUITING
BRA Santa Casa de Misericórdia de Ponta Grossa, Ponta Grossa
RECRUITING
Sociedade Hospitalar Angelina Caron, Campina Grande
RECRUITING
Hospital de Clinicas Porto Alegre, Porto Alegre
RECRUITING
Fundacao Felice Rosso - Hospital Felicio Rocho, Barro Preto
RECRUITING
Hospital Alemao Oswaldo Cruz, São Paulo
RECRUITING
Alberta Health Services, Edmonton
COMPLETED
Vancouver General Hospital, Vancouver
RECRUITING
Orillia Soldier's Memorial Hospital, Orillia
RECRUITING
Mackenzie Health, Richmond Hill
RECRUITING
The Charles Lemoyne Hospital, Longueuil
RECRUITING
Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke
RECRUITING
Red Deer Hospital;, Red Deer
RECRUITING
Humber River Hospital, Toronto
RECRUITING
Michael Garron Hospital, Toronto
RECRUITING
Trillium Health Partners, Toronto
RECRUITING
AURA Paris Plaisance, Paris
RECRUITING
Hadassah University, Jerusalem
RECRUITING
Shaare Zedek Medical Centre, Jerusalem
RECRUITING
Meir Hospital, Kfar Saba
RECRUITING
Sheba Hospital, Ramat Gan
COMPLETED
Auckland City Hospital, Auckland
COMPLETED
Christchurch Hospital, Christchurch
COMPLETED
Dunedin Hospital, Dunedin
COMPLETED
Waikato DHB, Hamilton
COMPLETED
Hawkes Bay Hospital, Hastings
COMPLETED
Middlemore Hospital, Otahuhu
COMPLETED
Waitematā Hospital, Takapuna
COMPLETED
Northland DHB, Whangarei
RECRUITING
Cambridge University Hospitals NHS Foundation Trust, Cambridge
RECRUITING
University Hospitals Plymouth NHS Trust, Plymouth
RECRUITING
Dorset County Hospital NHS Foundation Trust, Dorchester
RECRUITING
South Tyneside And Sunderland NHS Foundation Trust, Sunderland
RECRUITING
East and North Hertfordshire NHS Trust, Stevenage
RECRUITING
East Kent Hospitals University NHS Foundation Trust, Canterbury
RECRUITING
NHS Greater Glasgow and Clyde, Glasgow
RECRUITING
James Paget University Hospitals NHS Foundation Trust, Great Yarmouth
RECRUITING
NHS Lanarkshire, Airdrie
RECRUITING
South Tees Hospitals NHS Foundation Trust, Middlesbrough
RECRUITING
York and Scarborough Teaching Hospitals NHS Foundation Trust, York
RECRUITING
Nottingham University Hospitals NHS Trust, Nottingham
RECRUITING
NHS Highland, Inverness
RECRUITING
Shrewsbury and Telford Hospital NHS Trust, Shrewsbury
RECRUITING
Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield
RECRUITING
University Hospital of North Midlands NHS Trust, Stoke-on-Trent
RECRUITING
West Suffolk Hospital, Bury St Edmunds
RECRUITING
University Hospitals Sussex NHS Foundation Trust, Brighton
RECRUITING
Bradford Teaching Hospital NHS Foundation Trust, Bradford
RECRUITING
Wirral University Teaching Hospital NHS Foundation Trust, Birkenhead
RECRUITING
University Hospital Birmingham NHS foundation Trust, Birmingham
RECRUITING
Cardiff and Wales University Local Health Board, Cardiff
RECRUITING
North Cumbria Integrated Care NHS Foundation Trust, Carlisle
RECRUITING
Epsom and St Helier University Hospitals NHS Trust, Carshalton
RECRUITING
Gloucestershire Hospital NHS Foundation Trust, Cheltenham
RECRUITING
University Hospitals Coventry & Warwickshire, Coventry
RECRUITING
University Hospitals of Derby and Burton, Derby
RECRUITING
Doncaster and Bassetlaw Teaching Hospitals NHS Foundation Trust, Doncaster
RECRUITING
The Dudley Group NHS Foundation Trust, Dudley
RECRUITING
Royal Devon and Exeter NHS Foundation Trust, Exeter
RECRUITING
Hull University Teaching Hospital NHS Trust, Hull
RECRUITING
Ipswich Hospital (East Suffolk & North Essex Foundation Trust), Ipswich
RECRUITING
University Hospitals Of Leicester NHS Trust, Leicester
RECRUITING
Royal Liverpool University Hospitals, Liverpool
RECRUITING
University Hospital Aintree, Liverpool
RECRUITING
Guy's and St Thomas' NHS Foundation Trust, London
RECRUITING
King's College Hospital NHS Foundation Trust, London
RECRUITING
St George's University Hospitals NHS Foundation Trust, London
RECRUITING
Manchester University NHS Foundation Trust, Manchester
RECRUITING
The Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne
RECRUITING
Royal Berkshire NHS Foundation Trust, Reading
RECRUITING
Mid and South Essex NHS Foundation Trust, Southend-on-Sea
RECRUITING
The Royal Wolverhampton NHS Trust, Wolverhampton
RECRUITING
Foothills Hospital/ U of Calgary, Calgary
RECRUITING
St. Paul's Hospital, Vancouver
RECRUITING
Dalhousie University, Halifax
RECRUITING
Queen's University, Kingston
RECRUITING
London Health Sciences Centre, London
RECRUITING
Oakville Trafalgar Memorial Hospital, Oakville
RECRUITING
Lakeridge Health, Oshawa
RECRUITING
The Ottawa Hospital, Ottawa
RECRUITING
Scarborough Hospital Network, Scarborough Village
RECRUITING
St Michael's Hospital, Toronto
RECRUITING
University Health Network - University of Toronto, Toronto
RECRUITING
St. Joseph's Healthcare Hamilton, Toronto
RECRUITING
St. Joseph's Healthcare Toronto, Toronto
RECRUITING
McGill University Health Centre, Montreal
RECRUITING
Hopital Maisonneuve Rosemont, Montreal
RECRUITING
CHUM, Montreal
RECRUITING
Jewish General Hospital, Montreal
RECRUITING
Sacre Coeur Hospital, Montreal
RECRUITING
CHU de Quebec Universite Laval, Québec
RECRUITING
Centre hospitalier universitaire de Sherbrooke (CHUS), Sherbrooke
Collaborators (1)
National Health and Medical Research Council, Australia
OTHER
Applied Health Research Centre
OTHER
Cambridge University Hospitals NHS Foundation Trust
OTHER
University of Otago
OTHER
The University of Queensland
OTHER