180
Participants
Start Date
September 27, 2018
Primary Completion Date
June 30, 2020
Study Completion Date
June 30, 2020
FeFum fortified maize test meal
Maize porridge extrinsically labeled with 2 mg ferrous fumarate (58FeFum); only for iron deficient children (defined by plasma ferritin \<40 mikrogramm/L and/or sTfR \>8.3 mg/L); cereal staple foods, like maize, depending on milling, may be high in phytic acid, a potent iron absorption inhibitor
FeSO4 fortified LNS
self-made Lipid-based nutritional supplement (LNS) extrinsically fortified and labeled with 6 mg ferrous sulfate (57FeSO4); only for iron deficient children (defined by plasma ferritin \<40 mikrogramm/L and/or sTfR \>8.3 mg/L); LNS may be a better food matrix for iron supplementation compared to maize-based porridge; contains canola oil, peanut paste, milk powder, sugar, maltodextrin and palm stearin
FeSO4 supplement
170 mg iron tablets as FeSO4 (containing 55 mg of elemental iron) with 6 mg extrinsically labeled 57Fe; will be given together with a glass of water; only for iron deficient children (defined by plasma ferritin \<40 mikrogramm/L and/or sTfR \>8.3 mg/L);
FeSO4 fortified fruit juice
Fruit juice labeled with 12 mg 57Fe as FeSO4; in the group for iron sufficient children
Familiy Clinical Research Unit (FAMCRU), Cape Town
University of Stellenbosch
OTHER
Swiss Federal Institute of Technology
OTHER