Direct Oral Anticoagulants in Patients With Atrial Fibrillation (DOACs vs DOACs)

CompletedOBSERVATIONAL
Enrollment

227,579

Participants

Timeline

Start Date

November 30, 2016

Primary Completion Date

November 30, 2016

Study Completion Date

November 30, 2016

Conditions
Atrial FibrillationIschemic StrokeSystemic EmbolizationMajor BleedMyocardial InfarctionAll-cause Mortality
Interventions
DRUG

Apixaban (ATC B01AF02)

Exposure to apixaban (ATC B01AF02) will be defined as a new prescription for apixaban at cohort entry date in patients diagnosed with non-valvular atrial fibrillation. Patients are considered exposed until end of follow-up regardless of switch or interruption.

DRUG

Dabigatran (ATC B01AE07)

Exposure to dabigatran (ATC B01AE07) will be defined as a new prescription for dabigatran at cohort entry date in patients diagnosed with non-valvular atrial fibrillation. Patients are considered exposed until end of follow-up regardless of switch or interruption.

DRUG

Rivaroxaban (ATC B01AF01)

Exposure to rivaroxaban (ATC B01AF01) will be defined as a new prescription for rivaroxaban at cohort entry date in patients diagnosed with non-valvular atrial fibrillation. Patients are considered exposed until end of follow-up regardless of switch or interruption.

Trial Locations (1)

H2X 0A9

Centre de recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montreal

All Listed Sponsors
collaborator

Drug Safety and Effectiveness Network, Canada

OTHER

collaborator

Canadian Institutes of Health Research (CIHR)

OTHER_GOV

lead

Canadian Network for Observational Drug Effect Studies, CNODES

OTHER

NCT03568916 - Direct Oral Anticoagulants in Patients With Atrial Fibrillation (DOACs vs DOACs) | Biotech Hunter | Biotech Hunter