360
Participants
Start Date
July 3, 2018
Primary Completion Date
October 28, 2021
Study Completion Date
December 31, 2022
treatment1
"1. Acupoints:Liangqiu(ST34),Xuehai(SP10),Neixiyan(EX-LE4),Dubi(ST35),Yanglingquan (GB34)and Yinlingquan (SP9)~2. operation: the needles will be manipulated using techniques including lifting, thrusting, twisting, and rotating, until De Qi is achieved for 30 minutes."
treatment2
"1. Acupoints:Needling points are the same to the above group~2. operation: The electrode will be connected Neixiyan (EX-LE4) and Dubi (ST35) and electrode wire will be connected to the electro-acupuncture apparatus using dilatational wave with a frequency of 2/100 Hz, the current intensity is within participants'tolerance, for 30 minutes."
treatment3
"1. Acupoints:treating points are the same to the above group~2. Operation: During treatment, participants will choose to sit with knee buckling natural 90 degrees ,with the affected knee(s) exposed. Mild moxibustion are applied at the distance of 2-3 cm away from the skin of both the Neixiyan (EX-LE4) and Dubi (ST35) for 30 minutes."
treatment4
"1. Acupoints:Needling points are the same to the above group~2. Operation: Warm-needling acupuncture are applied at both Neixiyan (EX-LE4) and Dubi (ST35). That is to insert one zhuang(about 2cm)of Huai Qing Ai on the top of the needle, and burn the moxa at the lower end ,each acupoint applied 2 Zhuang for 30 minutes."
treatment5
"1. points:Sham Liangqiu(ST34),Sham Xuehai(SP10), Sham Neixiyan(EX-LE4), Sham Yanglingquan(GB34),Sham Yinlingquan (SP9)~2. Operation: Sham acupuncture with non-meridian and non-acupoint needling method, respectively acupuncture 1cm away lateral to the above sham acupoints with a 0.18 \* 25mm single-use needle with the depth of 1-2mm."
Celebrex
Drug: Celebrex (Celebrex, Capsules, Pfizer Pharmaceuticals Ltd), which will be applied 1 time daily( taken 0.2g one time orally ) Time of treatment :4 weeks Other Name: celecoxib
The third affiliated hospital of Zhejiang CMU, Hangzhou
The Third Affiliated hospital of Zhejiang Chinese Medical University
OTHER
Jiaxing TCM Hospital
UNKNOWN
Zhejiang Provincial Hospital of TCM
OTHER
Zhejiang Hospital
OTHER
Red Cross Hospital, Hangzhou, China
OTHER
Zhejiang Provincial Tongde Hospital
OTHER
Zhejiang Chinese Medical University
OTHER_GOV