FFR Driven Complete Revascularization Versus Usual Care in NSTEMI Patients and Multivessel Disease

NAActive, not recruitingINTERVENTIONAL
Enrollment

476

Participants

Timeline

Start Date

June 7, 2018

Primary Completion Date

July 21, 2025

Study Completion Date

July 31, 2027

Conditions
Coronary Artery DiseaseNSTEMI - Non-ST Segment Elevation MIFractional Flow Reserve, MyocardialMyocardial RevascularizationPercutaneous Coronary Intervention
Interventions
PROCEDURE

Ischemia driven revascularization

In the ischemia driven complete revascularisation strategy group all flow limiting (FFR ≤ 0.80) lesions will receive treatment by PCI and stenting during the index intervention

OTHER

Usual care group

In the randomised to usual care group the procedure will stop after the PCI of the culprit artery and the patient will be referred to his treating cardiologist and/ or heart team who will decide whether a staged PCI of the non- IRA artery should take place. If the treating cardiologist (after advise of the heart team) decides to perform the non-IRA PCI revascularisation, than such treatment should take place within six weeks from the primary PCI in order to count as a scheduled staged PCI procedure.

Trial Locations (9)

Unknown

Brno University Hospital, Brno

Gottsegen György Országos Kardiológiai Intézet, Budapest

Bacs-Kiskun Teaching Hospital, Kecskemét

Szeged University, Szeged

Jeroen Bosch Ziekenhuis, 's-Hertogenbosch

Zuyderland MC, Heerlen

Maastricht University Medical Centre, Maastricht

Radboud University Medical Centre, Nijmegen

Viecuri Medisch Centrum, Venlo

All Listed Sponsors
collaborator

Maastricht University Medical Center

OTHER

collaborator

Radboud University Medical Center

OTHER

collaborator

Jeroen Bosch Ziekenhuis

OTHER

collaborator

VieCuri Medical Centre

OTHER

collaborator

Gottsegen György Országos Kardiológiai Intézet

UNKNOWN

collaborator

Bács-Kiskun County Teaching Hospital

OTHER

collaborator

Brno University Hospital

OTHER

collaborator

Szeged University

OTHER

lead

Zuyderland Medisch Centrum

OTHER

NCT03562572 - FFR Driven Complete Revascularization Versus Usual Care in NSTEMI Patients and Multivessel Disease | Biotech Hunter | Biotech Hunter