140
Participants
Start Date
July 2, 2018
Primary Completion Date
September 30, 2020
Study Completion Date
September 30, 2020
Universal Posaconazole Prophylaxis
All patients assigned to this arm will start posaconazole between Day 4 and Day 14 post lung or heart-lung transplant for a minimum of 3 months.
Pre-emptive Posaconazole Therapy
Posaconazole will be started if a fungal pathogen is identified or there is serological evidence of a fungal pathogen in the absence of any evidence of invasive fungal disease for 3 months.
St. Vincent's Hospital, Sydney
Alfred Health, Melbourne
The Prince Charles Hospital, Brisbane
Lead Sponsor
Merck Sharp & Dohme LLC
INDUSTRY
Bayside Health
OTHER_GOV