A Trial of IW-3718 for 8 Weeks in Patients With Persistent Gastroesophageal Reflux Disease (GERD) Receiving Proton Pump Inhibitors (PPIs)

PHASE3TerminatedINTERVENTIONAL
Enrollment

495

Participants

Timeline

Start Date

June 20, 2018

Primary Completion Date

October 7, 2020

Study Completion Date

November 3, 2020

Conditions
Gastroesophageal Reflux Disease (GERD)
Interventions
DRUG

IW-3718

oral tablet

DRUG

placebo

oral tablet

DRUG

Standard-dose PPIs QD

background therapy

Trial Locations (99)

10003

Beth Israel Medical Center, New York

10016

Manhattan Medical Research Practice PLLC, New York

10021

Weill Cornell Medical College, New York

11021

NYU School of Medicine, Great Neck

14127

Orchard Park Family Practice, Orchard Park

15240

Veterans Research Foundation of Pittsburgh - NAVREF, Pittsburgh

20155

GI Associates Gainesville, Gainesville

21215

Alan A Rosen MD PA, Baltimore

21701

Elligo Health Research, Frederick

21742

Meritus Center For Clinical Research, Hagerstown

24073

New River Valley Research Institute, Christiansburg

24502

Blue Ridge Medical Research, Lynchburg

27262

Peters Medical Research, LLC, High Point

27405

Medication Management LLC, Greensboro

27607

Wake Endoscopy Center, Raleigh

27612

Wake Research Associates, LLC, Raleigh

28546

East Carolina Gastroenterology, Jacksonville

29203

Consultants of Gastroenterology, Columbia

30033

Atlanta Center For Gastroenterology PC, Decatur

31201

Gastroenterology Associates of Central Georgia, LLC, Macon

32224

Mayo Clinic Jacksonville - PPDS, Jacksonville

32256

Borland Groover Clinic, Jacksonville

32610

University of Florida, Gainesville

32720

Avail Clinical Research LLC, DeLand

33028

Pines Clinical Research Inc, Pembroke Pines

33125

Millennium Clinical Research Inc-Miami, Miami

33409

Palm Beach Research Center, West Palm Beach

33458

Health Awareness Inc - MRA, Jupiter

33756

West Central Gastroenterology, LLP, Clearwater

33782

DMI Research, Pinellas Park

34653

Advanced Research Institute, Inc, New Port Richey

34684

Advanced Gastroenterology Associates, LLC, Palm Harbor

34761

Legacy Clinical Solutions: Sensible HealthCare, LLC - BTC - PPDS, Ocoee

36207

Pinnacle Research Group, Anniston

36608

Alabama Medical Group, PC, Mobile

37232

Vanderbilt University Medical Center, Nashville

37421

WR - ClinSearch, LLC, Chattanooga

37601

Multi Specialty Clinical Research, Johnson City

38138

Gastro One, Germantown

38237

Advanced Gastroenterology-Union City, Union City

43213

Aventiv Research, Inc., Columbus

44060

Great Lakes Gastroenterology Research, LLC, Mentor

44195

Cleveland Clinic, Cleveland

45219

Consultants For Clinical Research Inc, Cincinnati

48047

Clinical Research Institute of Michigan, Chesterfield

50325

Iowa Digestive Disease Center, Clive

53215

Wisconsin Center for Advanced Research Division of GI Associates, Milwaukee

54601

Mayo Clinic Health System - Franciscan Healthcare - PPDS, La Crosse

55446

Minnesota Gastroenterology, P.A., Plymouth

60453

Avicenna-DM Clinical Research, Oak Lawn

63141

Clinical Research Professionals, Chesterfield

64131

Kansas City Gastroenterology and Hepatology, Kansas City

66217

West Glen GI, Shawnee Mission

66606

Cotton O'Neil Clinical Research Center, Topeka

70072

Tandem Clinical Research, LLC, Marrero

70360

CroNOLA, LLC., Houma

70471

Clinical Trials Management LLC, Mandeville

72117

Arkansas Gastroenterology, North Little Rock

72212

Applied Research Center, Little Rock

73112

Digestive Disease Specialists, Inc., Oklahoma City

75044

Digestive Health Associates of Texas, Garland

75231

Dallas VA Medical Center - NAVREF, Dallas

76092

Texas Digestive Disease Consultants, Southlake

77043

Biopharma Informatic Inc., Houston

77074

Southwest Clinical Trials, Houston

77084

Research Consultants, Houston

77090

Houston Digestive Diseases Clinic, Houston

77581

Pearland Physicians, Pearland

78209

Quality Research Inc, San Antonio

80045

University of Colorado Hospital, Aurora

84058

Aspen Clinical Research LLC - MRA, Orem

84405

Advanced Research Institute, Ogden

85018

Elite Clinical Studies, Phoenix

85712

Adobe Clinical Research LLC, Tucson

87108

Lovelace Scientific Resources Inc, Albuquerque

89511

Advanced Research Institute - Reno, Reno

91345

Facey Medical Foundation, Mission Hills

91910

GW Research, Inc., Chula Vista

92114

Precision Research Institute, San Diego

92123

Medical Associates Research Group, Inc., San Diego

92801

Anaheim Clinical Trials LLC - ERN-PPDS, Anaheim

92879

Kindred Medical Institute for Clinical Trials, LLC, Corona

94070

Digestive Care Center, San Carlos

94305

Stanford University School of Medicine, Stanford

95821

Northern California Research Corp, Sacramento

97232

Legacy Research Institute, Portland

98004

Washington Gastroenterology, Bellevue

06606

Gastroenterology Associates of Fairfield County, Bridgeport

06010

Connecticut Clinical Research Foundation, Bristol

06708

Chase Medical Research LLC, Waterbury

02114

Massachusetts General Hospital, Boston

02215

Beth Israel Deaconess Medical Center, Boston

08234

AGA Clinical Research Associates, LLC. - MRA, Egg Harbor

T5A 4L8

ALTA Clinical Research Inc, Edmonton

L1H 3K4

Taunton Surgical Centre, Oshawa

L4B 3P8

Digestive Health Clinic, Richmond Hill

M4N 3M5

Sunnybrook Health Sciences Centre, Toronto

L4L 4Y7

Toronto Digestive Disease Associates Inc, Vaughan

G1G 3Y8

Recherche Clinique Sigma, Inc., Québec

Sponsors
All Listed Sponsors
lead

Ironwood Pharmaceuticals, Inc.

INDUSTRY