HIV-1-Gag Conserved-Element DNA Vaccine (p24CE) Vaccine Study

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

45

Participants

Timeline

Start Date

March 26, 2019

Primary Completion Date

February 10, 2021

Study Completion Date

February 10, 2021

Conditions
HIV Infections
Interventions
BIOLOGICAL

p24CE1/2 pDNA vaccine

4 mg administered by one injection/electroporation

BIOLOGICAL

p24CE1/2 pDNA vaccine admixed with full-length p55^gag pDNA vaccine

2 mg p24CE1/2 pDNA admixed with 2 mg full-length p55\^gag pDNA administered by one injection/electroporation

BIOLOGICAL

Full-length p55^gag pDNA vaccine

4 mg full-length p55\^gag pDNA vaccine administered by one injection/electroporation

BIOLOGICAL

Placebo

1 mL placebo administered by one injection/electroporation

Trial Locations (15)

14642

University of Rochester Adult HIV Therapeutic Strategies Network CRS, Rochester

15213

University of Pittsburgh CRS, Pittsburgh

19104

Penn Therapeutics, CRS, Philadelphia

27599

Chapel Hill CRS, Chapel Hill

35294

Alabama CRS, Birmingham

37204

Vanderbilt Therapeutics (VT) CRS, Nashville

43210

Ohio State University CRS, Columbus

60611

Northwestern University CRS, Chicago

60612

Rush University CRS, Chicago

90035

UCLA CARE Center CRS, Los Angeles

94110

Ucsf Hiv/Aids Crs, San Francisco

02114

Massachusetts General Hospital CRS (MGH CRS), Boston

02115

Brigham and Women's Hospital Therapeutics Clinical Research Site (BWH TCRS) CRS, Boston

98104-9929

University of Washington AIDS CRS, Seattle

00935

Puerto Rico AIDS Clinical Trials Unit CRS, San Juan

All Listed Sponsors
lead

National Institute of Allergy and Infectious Diseases (NIAID)

NIH

NCT03560258 - HIV-1-Gag Conserved-Element DNA Vaccine (p24CE) Vaccine Study | Biotech Hunter | Biotech Hunter