D-PLEX 302: Efficacy and Safety of D-PLEX in the Prevention of Sternal Infection Post Cardiac Surgery

PHASE3TerminatedINTERVENTIONAL
Enrollment

2

Participants

Timeline

Start Date

December 17, 2019

Primary Completion Date

October 24, 2022

Study Completion Date

October 24, 2022

Conditions
Surgical Site InfectionSternal InfectionCardiac Surgery
Interventions
DRUG

D-PLEX

D-PLEX is a new formulation of extended release of Doxycycline (active ingredient)

OTHER

Standard of Care

"The SOC prophylactic antibiotic treatment will be consistent and standardized for all sites in the clinical study. is based on The society of thoracic surgeons practice guideline series: antibiotic prophylaxis in cardiac surgery, part II: antibiotic choice."

Trial Locations (3)

55902

Mayo Clinic, Rochester

77024

Memorial Hermann, Houston

Unknown

Soroka Medical Center, Beersheba

Sponsors

Lead Sponsor

All Listed Sponsors
lead

PolyPid Ltd.

INDUSTRY